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One set of cells clears away damaged bone, another lays down new tissue, and the two have to stay in step
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Compared with those fed the 0.3 mg Se/kg diet, pig fed 3.0 mg Se/kg diet showed up-regulations of SREBP1 (59%) and fatty acid synthase ( FASN ) (doubled) in the liver and peroxisome proliferator-activated receptor gamma ( PPARG ) and TRP53 (42–48%) in the muscle, and down-regulations of CYP7A1 (88%) in the liver and ACC1 (51%) and FASN (57%) in the muscle, respectively
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