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JCI - Dual targeting of the thioredoxin and glutathione systems in cancer and HIV

Research has shown that 7,8-dihydroxyflavone (7,8-DHF) can alleviate SZ-like symptoms by effectively mimicing the effect of brain-derived neurotrophic factor (BDNF) in the brain (Jaehne et al., 2021) to selectively activate tyrosine kinase receptor B (TrkB) (Gao et al., 2023)

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avium ATCC 25291 strain was cultured in 7H9 medium (Hi Media, Santa Maria, CA, USA) supplemented with albumin dextrose complex (ADC) (GeminiBio, West Sacramento, CA, USA) and incubated at 37 °C and grown until reaching the logarithmic growth phase (indicated by an optical density between 0.5 and 0.8 at A600)