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1,4 Adverse events ≥ 5% in SUSTAIN 5 8,10 AEs occurring in ≥ 5% of participants treated with Ozempic ® injection in SUSTAIN 5 Incidence of severe hypoglycemia was ≤1.5% across all placebo-controlled trials 1 Incidence of severe hypoglycemia or blood glucose-confirmed hypoglycemia (% of patients) was 8,10 : 8.3% with Ozempic ® 0.5 mg + basal insulin ± MET 10.7% with Ozempic ® 1 mg + basal insulin ± MET 5.3% with placebo + basal insulin ± MET Patients receiving Ozempic ® injection in combination with an insulin secretagogue (eg, sulfonylurea) or insulin may have an increased risk of hypoglycemia, including severe hypoglycemia 1 Adverse events ≥ 5% in SUSTAIN FORTE 4 AEs occurring in ≥ 5% of patients receiving Ozempic ® injection 1 mg and 2 mg in SUSTAIN FORTE In placebo-controlled trials, the most common adverse reactions reported in ≥5% of patients treated with Ozempic ® injection are nausea, vomiting, diarrhea, abdominal pain, and constipation 1 No new safety signals were identified