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This is accomplished through the controlled application of a selective pressure on the microbial population, in order to select evolved strains with specific phenotypes [61],[62]
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BPC-157 is proposed to increase fibroblast outgrowth and collagen deposition through FAK-paxillin signalling, while TB-500 is proposed to speed the migration of repair cells into the lesion by regulating actin polymerisation, which is the rationale for studying them together
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