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Schematic representation of the potential use of combinatorial therapies exploiting standard treatments [such as PI (proteasome inhibitors), IMiDs (immunomodulatory imide drugs), moAbs (monoclonal antibodies), and St (steroids)] in combination with molecules targeting c-MET or HGF (such as anti-c-MET-tyrosine-kinase inhibitors, neutralizing or competitive anti-HGF antibodies, miRNAs downmodulating c-MET, or siRNA silencing c-MET) to block downstream signals favoring survival, proliferation, and migration of MM cells

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That’s exactly what your tri-modality method is designed to do