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Probably, the most important glutathione S -conjugate transporters are multidrug resistance protein 1 (MRP1, ABCC1) and MRP2 (ABCC2) (Cole and Deeley, 2006, Nies and Keppler, 2007, Sibhatu et al., 2008, Slot et al., 2008, Cole, 2014)
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[5] In summary, pyridoxine may decrease the efficacy of certain medications (notably levodopa and some anticonvulsants), and various drugs can in turn precipitate vitamin Bβ deficiency
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