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Furthermore, the authors showed that miR-143/145 inhibited CRC cell proliferation in vitro , by inhibiting IGF1R expression highlighting their tumor suppressor activity in CRC, the importance of IGF1R in CRC pathogenesis, and underlying a novel regulatory network to fine-tune cell proliferation (87)
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Ning S, Zhang Z, Ren Y, Hou Y, Li D, Chen J, et al
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