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Developing novel detection techniques that are sensitive, selective, and economical is necessary to fulfill present requirements and ensure the appropriate handling of pharmaceutical materials in modern culture (Lim and Lord, 2002), gas chromatography-mass spectrometry (GCMS) (Deng et al., 2003), capillary electrophoresis (CE) (Krait et al., 2021), liquid chromatography-mass spectrometry (LC-MS) (Seger, 1946), and immunoassays are examples of traditional analytical methods for pharmaceutical detection that are well-established and have benefits like high compound separation efficiency, sensitivity, and low sample volume requirements (Soleymani and Golsanamluo, 2021)

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