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PGC-1α and its downstream regulatory factors (NRF-1, NRF-2, and TFAM) play a pivotal role in the regulation of the spinal cord, muscle, and adipose tissue of SOD1-G93A ALS model mice
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A development-stage preparation of BPC-157 designated PL14736 was the subject of early-phase clinical investigation as a candidate for inflammatory bowel disease, with supporting preclinical data reported on rat colocutaneous fistula models [9]
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