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Methamphetamine, he says, "is going to create probably the largest dump of dopamine in the brain than any other drug, at least in the short term," producing a hyperdopaminergic state where "every idea is a good idea and everything's about them and their goals." MDMA, by contrast, "there is no evidence that it's neurotoxic." The famous finding that MDMA caused neuron loss in non-human primates, published in Science , "was retracted because that laboratory accidentally injected methamphetamine, not MDMA." Huberman's read on the "holes in the brain" stories: "Probably wasn't MDMA