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Dose escalation studies were carried out in groups of 4 mice with matched doses of 0.1 µg, 1 µg, and 10 µg delivered at weeks 0 and 8 and bleeds were collected every 2 weeks for 18 weeks
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In preclinical models, Dihexa has shown the ability to increase synaptic markers like synaptophysin, improve neuronal counts in the hippocampus, and restore spatial memory and learning capacity in cognitively impaired animals
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