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Symptoms of blood clots in the legs or arms may include: Pain Swelling Tenderness Reddish skin color Warmth to touch Symptoms of a blood clot in the abdomen may include: Stomach swelling Pain Symptoms of a blood clot in the heart (heart attack) may include: Shortness of breath Chest pain Fatigue Lightheadedness Nausea Pain or discomfort in the arms, jaw, neck, or back Symptoms of a blood clot in the brain (stroke) may include: Severe headache Difficulty seeing Difficulty speaking Confusion Numbness or weakness in the face, arm, or leg Loss of balance Lack of coordination Symptoms of a blood clot in the lung (pulmonary embolism) may include: Chest pain Shortness of breath and other breathing issues Cough up blood Rapid heart rate Hyperviscosity syndrome is a problem that interferes with healthy blood flow