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Pain as an Integral Component of Wound Pathophysiology Regardless of the underlying cause, every wound is associated with varying degrees of pain, defined as “an unpleasant sensory and emotional experience associated with, or pretending to be associated with, actual or potential tissue damage” [30]
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These compounds have long been demonstrated to be the main excretion form of Cd [19] and Hg [20,21] in mammals and their toxicity is modulated by the nature of the metal-binding biothiol [22,23,24]
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