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Three species of parasitic helminths have been shown to contain cysteine S -conjugate β-lyase activity (Adcock et al., 1999)

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The activation of NADPH oxidase has been strongly associated with hypertension.[32] Oxidation or deficiency of tetrahydrobiopterin (BH4) and L-arginine which are two cofactors for endothelium-derived NO synthase (eNOS) action are associated with the uncoupling of the L-arginine-NO pathway that results in increased eNOS-mediated generation of superoxide and decreased formation of NO