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Consistent with this, we identified mTORC2 components—including mTOR, RICTOR, SIN1/MAPKAP1 (SIN1), and mLST8—demonstrating that mTORC2 is a novel SLAP target in CRC cells (Fig
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S -Adenosylhomocysteine, which is a product of these methyltransferases, gives rise to homocysteine
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