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70% fat, 20% protein, 10% carbohydrates) functions as an adipocyte-targeting adjuvant therapy, exerting antitumor effects through multimodal mechanisms by exploiting the 20–30-fold accelerated glucose-fermentative dependency of malignancies—which lack essential ketolytic enzymes—to force systemic lipid oxidation and ketogenesis that metabolically starves tumors, while simultaneously suppressing obesity-driven adipocyte hypertrophy through hypoglycemia and insulin reduction to attenuate proinflammatory cytokine secretion (e.g., TNF-α, IL-6), abrogate insulin/IGF-1 axis activation, and disrupt protumorigenic signaling