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82 For example, the key factors influencing AMP activity include specific amino acid residues, net charge, hydrophobicity, amphipathicity, and structural characteristics
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So, we recommend using SL vitamin B12 rather than oral and IM, especially in patients who do not tolerate IM injection and patients who need prolonged vitamin B12 supplementation, such as patients with long-term metformin use and patients with pernicious anemia or with gastro-duodenal resection [51–54]
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