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Measures of Disease Frequency of: HLA-B8 HLA-DR3 HLA-Drw52a Ischemic damage to the biliary ducts Bacterial infection leading to chronic or recurrent cholangitis Pathophysiology Environmental insult in susceptible individuals → cholangiocyte activation → cytokine production → perpetual inflammatory response Chronic periductal inflammation Inflammation Inflammation is a complex set of responses to infection and injury involving leukocytes as the principal cellular mediators in the body’s defense against pathogenic organisms
cat:GLP-1
Size:65 x 450-500
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