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α-Lipoic Acid Strengthens the Antioxidant Barrier and Reduces Oxidative, Nitrosative, and Glycative Damage, as well as Inhibits Inflammation and Apoptosis in the Hypothalamus but Not in the Cerebral Cortex of Insulin-Resistant Rats

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In these cell systems, the apparent involvement of TAL in the homeostasis of cell reduced state is concomitant with a low activity of catalase, another antioxidant enzyme whose activity could be restored by NADPH supplementation [76]