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The modeling of TM16-TM17 allows the identification of putative residues for the stimulated transport of GSH The above results led us to conclude that among the expressed chimeras, M8 is the most significantly affected both for inducing CS and for its GSH-dependent transport activity
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Remodeling of calcium signaling is closely associated with the development of hormone-sensitive, castration-resistant, and highly aggressive PCa subtypes, directly regulating the responsiveness of PCa to anti-androgen therapies
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