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Specifically, to assess basal analgesia, (i) the first assessment (time "0") was preceded by the application of morphine or saline 30 min before (time "-30 min"), then by the application of the gastric pentadecapeptide BPC 157 or naloxone or saline 20 min before (time "-20 min"), and finally, by the application of the saline 10 min before (time "-10 min")
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The intracellular metabolite extracts and 2 mL of spent culture medium containing extracellular metabolites were freeze-dried (BenchTop K manifold freeze dryer, VirTis) prior chemical derivatisation
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